I don't think the author of this piece quite grasps what "the selfish gene" actually is:
If it’s been said once, it’s been said a thousand times, nice guys finish last. But why is it that women choose dominance every time over niceness, dooming notions of sexual equality to dismal failure?

The Selfish Gene” theory could explain the tendency of women not only to marry up, but to completely disregard the bottom 4/5 of men as potential suitors as The Pareto Principle suggests and eyewitness evidence in any club in America will illustrate. Here’s a simple definition of The Selfish Gene:

A lineage is expected to evolve to maximize its inclusive fitness—the number of copies of its genes passed on globally (rather than by a particular individual).

This theory is bad news for men in a sexual market that has shifted to look more like a jungle than a civilization since the advent of “women’s liberation” a.k.a. feminism. The Realtalk translation of that very effete sounding definition of The Selfish Gene works out to: Women want to fuck the winners, and they will fuck over the losers.

Women have evolved to disregard and even harbor contempt for “inferior” DNA. In a cruel world in which survival of the fittest has been the rule from day one over 4 billion years ago when life began to form in the slime, being a nice boy doesn’t cut it. Women, more than men, are beholden to the influences of The Selfish Gene, and though we may lament its effects on our sexual and familial prospects as men there are sound biological reasons women have evolved to be ruthless when it comes to choosing sexual partners.
As much as it pains me to say this, a little reading of Richard Dawkins is in order here. Selfish gene theory will not explain hypergamy because there is no known hypergamous gene or even combination of genes that lead women to behave in this manner.

Indeed, the "quality" theory underlying hypergamy tends to conflict with the idea of the selfish gene.